Lab-on-Chip Cytometry Based on Magnetoresistive Sensors for Bacteria Detection in Milk

Sensors

Ana C. Fernandes¹  Carla M. Duarte¹  Filipe A. Cardoso¹  Ricardo. Bexiga²  Susana. Cardoso¹ 

[1] INESC–MN—Instituto de Engenharia de Sistemas e Computadores–Microsistemas e Nanotecnologias and IN—Institute of Nanoscience and Nanotechnology, Rua Alves Redol 9, 1000-029 Lisbon, Portugal; E-Mails:;CIISA, Veterinary Medicine Faculty, Technical University of Lisbon, Av. da Universidade Técnica, 1300-477 Lisbon, Portugal; E-Mail:

关键词: cytometer;    microfluidic;    magnetoresistive sensor;    milk;    Streptococcus agalactiae;   

DOI  :  10.3390/s140815496

来源: mdpi

【 摘 要 】

Flow cytometers have been optimized for use in portable platforms, where cell separation, identification and counting can be achieved in a compact and modular format. This feature can be combined with magnetic detection, where magnetoresistive sensors can be integrated within microfluidic channels to detect magnetically labelled cells. This work describes a platform for in-flow detection of magnetically labelled cells with a magneto-resistive based cell cytometer. In particular, we present an example for the validation of the platform as a magnetic counter that identifies and quantifies Streptococcus agalactiae in milk.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.