Synthetic Biology and Metabolic Engineering for Marine Carotenoids: New Opportunities and Future Prospects

Marine Drugs

Chonglong Wang¹  Jung-Hun Kim¹ 

[1] Division of Applied Life Science (BK21 Plus), PMBBRC, Gyeongsang National University, Jinju 660-701, Korea;

关键词: marine carotenoids;    carotenoid synthesis;    carotenoid modification;    metabolic engineering;    synthetic biology;    protein engineering;   

DOI  :  10.3390/md12094810

来源: mdpi

【 摘 要 】

Carotenoids are a class of diverse pigments with important biological roles such as light capture and antioxidative activities. Many novel carotenoids have been isolated from marine organisms to date and have shown various utilizations as nutraceuticals and pharmaceuticals. In this review, we summarize the pathways and enzymes of carotenoid synthesis and discuss various modifications of marine carotenoids. The advances in metabolic engineering and synthetic biology for carotenoid production are also reviewed, in hopes that this review will promote the exploration of marine carotenoid for their utilizations.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.