Hydrogenations without Hydrogen: Titania Photocatalyzed Reductions of Maleimides and Aldehydes

Molecules

David W. Manley¹  Luca Buzzetti¹  Andrew MacKessack-Leitch¹ 

关键词: photocatalysis;    reduction;    titania;    maleimides;    aldehydes;   

DOI  :  10.3390/molecules190915324

来源: mdpi

【 摘 要 】

A mild procedure for the reduction of electron-deficient alkenes and carbonyl compounds is described. UVA irradiations of substituted maleimides with dispersions of titania (Aeroxide P25) in methanol/acetonitrile (1:9) solvent under dry anoxic conditions led to hydrogenation and production of the corresponding succinimides. Aromatic and heteroaromatic aldehydes were reduced to primary alcohols in similar titania photocatalyzed reactions. A mechanism is proposed which involves two proton-coupled electron transfers to the substrates at the titania surface.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.