Two New Quinochalcone C-Glycosides from the Florets of Carthamus tinctorius

International Journal of Molecular Sciences

Shijun Yue¹  Yuping Tang¹  Chengmei Xu¹  Shujiao Li¹  Yue Zhu¹ 

[1] Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China; E-Mails:

关键词: Carthamus tinctorius;    Hong hua;    quinochalcone C-glycosides;    hydroxysafflor yellow B;    hydroxysafflor yellow C;    anti-oxidative activity;   

DOI  :  10.3390/ijms150916760

来源: mdpi

【 摘 要 】

Two new quinochalcone C-glycosides, named hydroxysafflor yellow B (1) and hydroxysafflor yellow C (2), along with two known quinochalcone C-glycosides, safflomin C (3) and saffloquinoside C (4), and one known flavanone, (2R)-4',5-dihydroxyl-6,7-di-O-β-d-glucopyranosyl flavanone (5), were isolated from the florets of Carthamus tinctorius. Their structures were determined by extensive spectroscopic (UV, IR, HR-ESI-MS, 1D and 2D NMR) analyses. In addition, these quinochalcone C-glycosides together with hydroxysafflor yellow A and anhydrosafflor yellow B were evaluated for their anti-oxidative effects against H₂O₂-induced cytotoxicity in cultured H9c2 cells. Among them, compound 2 exhibited significant anti-oxidative effects.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.