Stem Cell Treatment for Alzheimer’s Disease

International Journal of Molecular Sciences

Ming Li²  Kequan Guo¹  Susumu Ikehara² 

[1] Department of Cardiac Surgery, Beijing Institute of Heart, Lung & Blood Vessel Disease, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing 100029, China; E-Mail:;Department of Stem Cell Disorders, Kansai Medical University, 2-5-1 Shinmachi, Hirakata City, Osaka 573-1010, Japan; E-Mail:

关键词: Alzheimer’s disease;    stem cell therapy;    oxidative stress;    neurodegeneration;   

DOI  :  10.3390/ijms151019226

来源: mdpi

【 摘 要 】

Alzheimer’s disease (AD) is a progressive and neurodegenerative disorder that induces dementia in older people. It was first reported in 1907 by Alois Alzheimer, who characterized the disease as causing memory loss and cognitive impairment. Pathologic characteristics of AD are β-amyloid plaques, neurofibrillary tangles and neurodegeneration. Current therapies only target the relief of symptoms using various drugs, and do not cure the disease. Recently, stem cell therapy has been shown to be a potential approach to various diseases, including neurodegenerative disorders, and in this review, we focus on stem cell therapies for AD.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.