N'-[2-(7,8-Dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylidene]-4-nitrobenzohydrazide

Molbank

Masayuki Morikawa¹  Katsuhito Kino¹  Eriko Asada¹  Kosuke Katagiri¹  Kanami Mori-Yasumoto¹  Masayo Suzuki¹  Takanobu Kobayashi¹ 

[1]Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, Sanuki, Kagawa 769-2193, Japan

关键词: flavin;    Nuclear factor-κB;    inhibitor;    DNA binding;   

DOI  :  10.3390/M836

来源: mdpi

【 摘 要 】

The title compound, N'-[2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin- 10(2H)-yl)ethylidene]-4-nitrobenzohydrazide (1), was obtained by the reaction of formylmethylflavin and p-nitrobenzohydrazide. The product 1 inhibited the DNA binding of nuclear factor-κB, and was characterized by ¹H-NMR, ¹³C-NMR, electrospray ionization mass spectrometry, elemental analysis, IR and UV.

【 授权许可】

CC BY   
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