A New Phenolic Glycoside from the Barks of Cinnamomum cassia

Molecules

Junfen Zeng²  Yongbo Xue³  Yongji Lai³  Guangmin Yao³  Zengwei Luo³  Yonghui Zhang³  Jinwen Zhang¹ 

[1] Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China;Department of Pharmacy, Renmin Hospital of Wuhan University, Wuhan 430060, China;Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

关键词: Cinnamomum cassia;    phenolic glycoside;    immunosuppressive activities;   

DOI  :  10.3390/molecules191117727

来源: mdpi

【 摘 要 】

A new phenolic glycoside (1), named methyl 2-phenylpropanoate-2-O-β-d-apiofuranosyl-(1→6)-O-β-d–glucopyranoside, was isolated from the barks of Cinnamomum cassia, along with three known phenolic glycosides and four known lignan glycosides. The structure of 1 was elucidated by extensive interpretation of spectroscopic data and chemical method. Selected compounds were evaluated for their immunosuppressive activities against murine lymphocytes. Compounds 1, 2, 6 and 8 exhibited differential inhibition against ConA-induced T cells proliferation.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.