The Influence of Dietary Fat on Liver Fat Accumulation

Nutrients

Charlotte J. Green¹ 

[1] Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK; E-Mail

关键词: dietary fat;    liver;    steatosis;    NAFLD;    VLDL-TG;    human;   

DOI  :  10.3390/nu6115018

来源: mdpi

【 摘 要 】

Obesity is a known risk factor for the development of non-alcoholic fatty liver disease (NAFLD); however, it has been suggested that dietary fat, both amount and composition, may play a pivotal role in its development, independent of body fatness. Studies that have investigated the role of dietary fat on liver fat accumulation are reasonably sparse. We review here the available work that has investigated the impact of dietary fat: amount, composition and frequency, on liver fat accumulation in human observational and intervention studies. Overall, it would seem that total calorie consumption, rather than dietary fat composition, is an important factor in the development of fatty liver disease in humans.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.