A Review of Recent Research Progress on the Astragalus Genus

Molecules

Xiaoxia Li²  Lu Qu²  Yongzhe Dong²  Lifeng Han¹  Erwei Liu¹  Shiming Fang¹  Yi Zhang²  Tao Wang² 

[1]Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 312 Anshan Road, Nankai District, Tianjin 300193, China

[2] E-Mails:

[3]Tianjin State Key Laboratory of Modern Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin, 300193, China

[4] E-Mails:

关键词: traditional Chinese medicines;    Astragalus genus;    phytochemistry;    biological activities;    analyses;   

DOI  :  10.3390/molecules191118850

来源: mdpi

【 摘 要 】

Astragalus L., is one of the largest genuses of flowering plants in the Leguminosae family. Roots of A. membranaceus Bge. var. mongholicus (Bge.) Hsiao, A. membranaceus (Fisch.) Bge. and its processed products are listed in the China Pharmacopeia for “qi deficiency” syndrome treatment. However, more and more researches on other species of Astragalus have been conducted recently. We summarize the recent researches of Astragalus species in phytochemistry and pharmacology. More than 200 constituents, including saponins and flavonoids, obtained from 46 species of Astragalus genus were collected for this article. In pharmacological studies, crude extracts of Astragalus, as well as isolated constituents showed anti-inflammatory, immunostimulant, antioxidative, anti-cancer, antidiabetic, cardioprotective, hepatoprotective, and antiviral activities. The goal of this article is to provide an overview of chemical and pharmacological studies on the Astragalus species over the last 10 years, which could be of value to new drug or food supplement research and development.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.