The Chemistry of Curcumin: From Extraction to Therapeutic Agent

Molecules

Kavirayani Indira Priyadarsini¹ 

[1]Radiation & Photochemistry Division, Bhabha Atomic Research Centre, Mumbai 400085, India

[2] E-Mail

关键词: curcumin;    extraction;    synthesis;    degradation;    metal chelation;    nanoformulation;   

DOI  :  10.3390/molecules191220091

来源: mdpi

【 摘 要 】

Curcumin, a pigment from turmeric, is one of the very few promising natural products that has been extensively investigated by researchers from both the biological and chemical point of view. While there are several reviews on the biological and pharmacological effects of curcumin, chemistry reviews are comparatively scarcer. In this article, an overview of different aspects of the unique chemistry research on curcumin will be discussed. These include methods for the extraction from turmeric, laboratory synthesis methods, chemical and photochemical degradation and the chemistry behind its metabolism. Additionally other chemical reactions that have biological relevance like nucleophilic addition reactions, and metal chelation will be discussed. Recent advances in the preparation of new curcumin nanoconjugates with metal and metal oxide nanoparticles will also be mentioned. Directions for future investigations to be undertaken in the chemistry of curcumin have also been suggested.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.