Au-Nanomaterials as a Superior Choice for Near-Infrared Photothermal Therapy

Molecules

Fahmida Jabeen¹  Muhammad Najam-ul-Haq¹  Rabia Javeed¹  Christian W. Huck²  Guenther K. Bonn² 

[1] Division of Analytical Chemistry, Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan; E-Mails:;Institute of Analytical Chemistry and Radiochemistry, Leopold-Franzens University, Innrain 80-82. Innsbruck 6020, Austria; E-Mails:

关键词: near-infrared spectroscopy;    nanoparticles/materials;    therapy monitoring;   

DOI  :  10.3390/molecules191220580

来源: mdpi

【 摘 要 】

Photothermal therapy (PPT) is a platform to fight cancer by using multiplexed interactive plasmonic nanomaterials as probes in combination with the excellent therapeutic performance of near-infrared (NIR) light. With recent rapid developments in optics and nanotechnology, plasmonic materials have potential in cancer diagnosis and treatment, but there are some concerns regarding their clinical use. The primary concerns include the design of plasmonic nanomaterials which are taken up by the tissues, perform their function and then clear out from the body. Gold nanoparticles (Au NPs) can be developed in different morphologies and functionalized to assist the photothermal therapy in a way that they have clinical value. This review outlines the diverse Au morphologies, their distinctive characteristics, concerns and limitations to provide an idea of the requirements in the field of NIR-based therapeutics.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.