Synthesis and Degradation of Schiff Bases Containing Heterocyclic Pharmacophore

International Journal of Molecular Sciences

Ionuţ Ledeţi²  Anda Alexa³  Vasile Bercean⁴  Gabriela Vlase¹  Titus Vlase¹  Lenuᘺ-Maria Şuta²  Adriana Fuliaş² 

[1] Research Centre for Thermal Analysis in Environmental Problems, West University of Timişoara, Timisoara 300115, Romania; E-Mails:;Faculty of Pharmacy, Victor Babeş University of Medicine and Pharmacy, 2 Eftimie Murgu, Timisoara 300041, Romania; E-Mails:;Faculty of Medicine, Victor Babeş University of Medicine and Pharmacy, 2 Eftimie Murgu, Timisoara 300041, Romania; E-Mail:;Faculty of Industrial Chemistry and Environmental Engineering, Politehnica University of Timişoara, 6 Carol Telbisz, Timisoara 300001, Romania; E-Mail:

关键词: Schiff base;    synthesis;    triazole;    thermal behavior;    kinetic study;   

DOI  :  10.3390/ijms16011711

来源: mdpi

【 摘 要 】

This paper reports on the synthesis and characterization of two Schiff bases bearing 1,2,4-triazolic moieties, namely 4H-4-(2-hydroxy-benzylidene-amino)-5-benzyl-3-mercapto-1,2,4-triazole and 4H-4-(4-nitro-benzylidene-amino)-5-benzyl-3-mercapto-1,2,4-triazole using thin layer chromatography, melting interval, elemental analysis, spectroscopy and thermal stability studies.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.