Age-Related Macular Degeneration: Advances in Management and Diagnosis

Journal of Clinical Medicine

Yoshihiro Yonekawa²  Joan W. Miller²  Ivana K. Kim¹  Lindsay Farrer² 

[1] Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA;

关键词: age-related macular degeneration;    choroidal neovascularization;    fundus autofluorescence;    fluorescein angiography;    optical coherence tomography;    retina;    vascular endothelial growth factor;    visual impairment;   

DOI  :  10.3390/jcm4020343

来源: mdpi

【 摘 要 】

Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in older populations in industrialized nations. AMD is a late-onset deterioration of photoreceptors and retinal pigment epithelium in the central retina caused by various environmental and genetic factors. Great strides in our understanding of AMD pathogenesis have been made in the past several decades, which have translated into revolutionary therapeutic agents in recent years. In this review, we describe the clinical and pathologic features of AMD and present an overview of current diagnosis and treatment strategies.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.