Lectins with Potential for Anti-Cancer Therapy

Molecules

Tammy Yau¹  Xiuli Dan²  Charlene Cheuk Wing Ng²  Tzi Bun Ng² 

[1] Department of Neurobiology, Physiology, and Behavior, University of California, Davis, CA 95616, USA; E-Mail:;School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China; E-Mails:

关键词: lectins;    cancer cells;    apoptosis;    autophagy;   

DOI  :  10.3390/molecules20033791

来源: mdpi

【 摘 要 】

This article reviews lectins of animal and plant origin that induce apoptosis and autophagy of cancer cells and hence possess the potential of being developed into anticancer drugs. Apoptosis-inducing lectins encompass galectins, C-type lectins, annexins, Haliotis discus discus lectin, Polygonatum odoratum lectin, mistletoe lectin, and concanavalin A, fucose-binding Dicentrarchus labrax lectin, and Strongylocentrotus purpuratus lectin, Polygonatum odoratum lectin, and mistletoe lectin, Polygonatum odoratum lectin, autophagy inducing lectins include annexins and Polygonatum odoratum lectin.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.