Biomechanical Evaluation of Ti-Nb-Sn Alloy Implants with a Low Young’s Modulus

International Journal of Molecular Sciences

Kenta Takahashi³  Naru Shiraishi³  Risa Ishiko-Uzuka³  Takahisa Anada²  Osamu Suzuki²  Hiroshi Masumoto¹  Keiichi Sasaki³ 

[1] Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, Aramaki aza Aoba 6-3, Aoba-ku, Sendai 980-8578, Japan; E-Mail:;Division of Craniofacial Function Engineering, Tohoku University Graduate School of Dentistry, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8577, Japan; E-Mails:;Division of Advanced Prosthetic Dentistry, Tohoku University Graduate School of Dentistry, Tohoku University, 4-1 Seiryo-machi, Aoba-ku, Sendai 980-8577, Japan; E-Mails:

关键词: low Young’s modulus;    Ti-Nb-Sn alloy;    implant;   

DOI  :  10.3390/ijms16035779

来源: mdpi

【 摘 要 】

Dental implants are widely used and are a predictable treatment in various edentulous cases. Occlusal overload may be causally related to implant bone loss and a loss of integration. Stress concentrations may be diminished using a mechanobiologically integrated implant with bone tissue. The purpose of this study was to investigate the biomechanical behavior, biocompatibility and bioactivity of a Ti-Nb-Sn alloy as a dental implant material. It was compared with cpTi. Cell proliferation and alkaline phosphatase (ALP) activity were quantified. To assess the degree of osseointegration, a push-in test was carried out. Cell proliferation and ALP activity in the cells grown on prepared surfaces were similar for the Ti-Nb-Sn alloy and for cpTi in all the experiments. A comparison between the Ti-Nb-Sn alloy implant and the cpTi implant revealed that no significant difference was apparent for the push-in test values. These results suggest that implants fabricated using Ti-Nb-Sn have a similar biological potential as cpTi and are capable of excellent osseointegration.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.