Bio-Optics Based Sensation Imaging for Breast Tumor Detection Using Tissue Characterization

Sensors

Jong-Ha Lee²  Yoon Nyun Kim¹  Hee-Jun Park² 

[1] Department of Internal Medicine, Dongsan Medical Center, Keimyung University, 1095, Dalgubeol-daero, Daegu 704-701, Korea; E-Mail:;Department of Biomedical Engineering, School of Medicine, Keimyung University, 1095, Dalgubeol-daero, Daegu 704-701, Korea; E-Mail:

关键词: tumor detection;    artificial palpation;    lesion characterization;    tactile sensor;    biomimetic sensor;    Young’s modulus;   

DOI  :  10.3390/s150306306

来源: mdpi

【 摘 要 】

The tissue inclusion parameter estimation method is proposed to measure the stiffness as well as geometric parameters. The estimation is performed based on the tactile data obtained at the surface of the tissue using an optical tactile sensation imaging system (TSIS). A forward algorithm is designed to comprehensively predict the tactile data based on the mechanical properties of tissue inclusion using finite element modeling (FEM). This forward information is used to develop an inversion algorithm that will be used to extract the size, depth, and Young's modulus of a tissue inclusion from the tactile data. We utilize the artificial neural network (ANN) for the inversion algorithm. The proposed estimation method was validated by a realistic tissue phantom with stiff inclusions. The experimental results showed that the proposed estimation method can measure the size, depth, and Young's modulus of a tissue inclusion with 0.58%, 3.82%, and 2.51% relative errors, respectively. The obtained results prove that the proposed method has potential to become a useful screening and diagnostic method for breast cancer.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.