In Vitro Corrosion and Cytocompatibility Properties of Nano-Whisker Hydroxyapatite Coating on Magnesium Alloy for Bone Tissue Engineering Applications

International Journal of Molecular Sciences

Huawei Yang²  Xueyu Yan²  Min Ling³  Zuquan Xiong¹  Caiwen Ou⁴  Wei Lu³ 

[1] Department of Urology, Huashan Hospital, Fudan University, Shanghai 200031, China;Departmentof Dentistry, Shanghai Tenth People’s Hospital, Tongji University, Shanghai 200072, China; E-Mails:;Shanghai Key Laboratory of Development and Application for Metal-Functional Materials, School of Materials Science and Engineering, Tongji University, Shanghai 201804, China; E-Mail:;Department of Science and Technology, Southern Medical University, Guangzhou 510515, China; E-Mail:

关键词: biodegradable Mg alloy;    hydroxyapatite;    hydrothermal process;   

DOI  :  10.3390/ijms16036113

来源: mdpi

【 摘 要 】

We report here the successful fabrication of nano-whisker hydroxyapatite (nHA) coatings on Mg alloy by using a simple one-step hydrothermal process in aqueous solution. The nHA coating shows uniform structure and high crystallinity. Results indicate that nHA coating is promising for improving the in vitro corrosion and cytocompatibility properties of Mg-based implants and devices for bone tissue engineering. In addition, the simple hydrothermal deposition method used in the current study is also applicable to substrates with complex shapes or surface geometries.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.