Microstructure Evolution and Mechanical Properties Improvement in Liquid-Phase-Sintered Hydroxyapatite by Laser Sintering

Materials

Songlin Duan¹  Pei Feng²  Chengde Gao²  Tao Xiao³  Kun Yu⁴  Cijun Shuai²  Shuping Peng¹ 

[1] Hunan Provincial Tumor Hospital and the Affiliated Tumor Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, China;State Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China; E-Mails:;Orthopedic Biomedical Materials Institute, Central South University, Changsha 410083, China; E-Mail:;School of Materials Science and Engineering, Central South University, Changsha 410083, China; E-Mail:

关键词: liquid phase sintering;    laser sintering;    microstructure;    mechanical properties;    hydroxyapatite;   

DOI  :  10.3390/ma8031162

来源: mdpi

【 摘 要 】

CaO-Al₂O₃-SiO₂ (CAS) as a liquid phase was introduced into hydroxyapatite (HAp) to prepare bone scaffolds. The effects of the CAS content (1, 2, 3, 4 and 5 wt%) on microstructure and mechanical properties of HAp ceramics were investigated. The optimal compression strength, fracture toughness and Vickers hardness reached 22.22 MPa, 1.68 MPa·m^1/2 and 4.47 GPa when 3 wt% CAS was added, which were increased by 105%, 63% and 11% compared with those of HAp ceramics without CAS, respectively. The improvement of the mechanical properties was attributed to the improved densification, which was caused by the solid particle to rearrange during liquid phase sintering. Moreover, simulated body fluid (SBF) study indicated the HAp ceramics could maintain the mechanical properties and form a bone-like apatite layer when they were immersed in SBF. Cell culture was used to evaluate biocompatibility of the HAp ceramics. The results demonstrated MG-63 cells adhered and spread well.

【 授权许可】

CC BY   
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