Journal of Functional Biomaterials | |
Influence of Implant Surface Topography on Primary Stability in a Standardized Osteoporosis Rabbit Model Study | |
Hiroshi Oue3  Kazuya Doi3  Yoshifumi Oki3  Yusuke Makihara3  Takayasu Kubo3  Vittoria Perrotti1  Adriano Piattelli1  Yasumasa Akagawa2  Kazuhiro Tsuga3  | |
[1] Department of Medical, Oral and Biotechnological Sciences, Chieti-Pescara University, Chieti-Via dei Vestini, 31, Chieti 66100, Italy; E-Mails:;Department of Prosthetic Dentistry School of Dentistry, Ohu University, 31-1 sankakudo, Kooriyama, Fukushima 963-8611, Japan; E-Mail:;Department of Advanced Prosthodontics, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan; E-Mails: | |
关键词: primary stability; osteoporosis; glucocorticoid; implant surface; rabbit model; | |
DOI : 10.3390/jfb6010143 | |
来源: mdpi | |
【 摘 要 】
Evaluating primary stability is important to predict the prognosis of dental implant treatment. Primary stability is decreased in a low bone density site such as osteoporosis. However, it is difficult to apply in small animal and the effect of the different implant surface topography for the primary stability at low bone density site has not yet fully been investigated. The purpose of the present study was to evaluate the influence of implant surface topography on primary stability in a standardized osteoporosis animal model. Six rabbits underwent ovariectomy and administrated glucocorticoid to induce an osteoporosis model. Sham-operations were performed in additional six rabbits. Implants with machined or oxidized-surfaces were inserted into the femur epiphyses and insertion torque (IT) and implant stability quotient (ISQ) were measured. In sham model, the IT and ISQ did not differ significantly between the both implant. However, the IT value of oxidized-surface implant was significantly higher than that of the machined implant in the osteoporosis model. Meanwhile, ISQ did not significantly differ between the machined and oxidized-surfaced implants. In conclusion, the IT of implants is higher with rough than with smooth surfaces but that there are no differences in ISQ value between different surfaces in a standardized osteoporosis bone reduced rabbit model.
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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