Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan

Toxins

Miguel Moreno¹  Ernest Giralt¹ 

关键词: bee;    wasp;    venom;    melittin;    apamin;    mastoparan;   

DOI  :  10.3390/toxins7041126

来源: mdpi

【 摘 要 】

While knowledge of the composition and mode of action of bee and wasp venoms dates back 50 years, the therapeutic value of these toxins remains relatively unexploded. The properties of these venoms are now being studied with the aim to design and develop new therapeutic drugs. Far from evaluating the extensive number of monographs, journals and books related to bee and wasp venoms and the therapeutic effect of these toxins in numerous diseases, the following review focuses on the three most characterized peptides, namely melittin, apamin, and mastoparan. Here, we update information related to these compounds from the perspective of applied science and discuss their potential therapeutic and biotechnological applications in biomedicine.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.