Enteral Nutrition in Pancreaticoduodenectomy: A Literature Review

Nutrients

Salvatore Buscemi¹  Giuseppe Damiano³  Vincenzo D. Palumbo²  Gabriele Spinelli²  Silvia Ficarella²  Giulia Lo Monte⁴  Antonio Marrazzo² 

[1] School of Oncology and Experimental Surgery, University of Palermo, via Del Vespro 129, 90127 Palermo, Italy;Department of Surgical, Oncological and Dentistry Studies, University of Palermo, via Del Vespro 129, 90127 Palermo, Italy; E-Mails:;“P.Giaccone”, University Hospital, School of Medicine, School of Biotechnology, University of Palermo, via Del Vespro 129, 90127 Palermo, Italy; E-Mail:;School of Biotechnology, University of Palermo, via Del Vespro 129, 90127 Palermo, Italy; E-Mail:

关键词: Enteral nutrition;    pancreaticoduodenectomy;    delayed gastric emptying;    postoperative pancreatic fistula;    postpancreatectomy hemorrhage;   

DOI  :  10.3390/nu7053154

来源: mdpi

【 摘 要 】

Pancreaticoduodenectomy (PD) is considered the gold standard treatment for periampullory carcinomas. This procedure presents 30%–40% of morbidity. Patients who have undergone pancreaticoduodenectomy often present perioperative malnutrition that is worse in the early postoperative days, affects the process of healing, the intestinal barrier function and the number of postoperative complications. Few studies focus on the relation between enteral nutrition (EN) and postoperative complications. Our aim was to perform a review, including only randomized controlled trial meta-analyses or well-designed studies, of evidence regarding the correlation between EN and main complications and outcomes after pancreaticoduodenectomy, as delayed gastric emptying (DGE), postoperative pancreatic fistula (POPF), postpancreatectomy hemorrhage (PPH), length of stay and infectious complications. Several studies, especially randomized controlled trial have shown that EN does not increase the rate of DGE. EN appeared safe and tolerated for patients after PD, even if it did not reveal any advantages in terms of POPF, PPH, length of stay and infectious complications.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.