Bioactive Wollastonite-Diopside Foams from Preceramic Polymers and Reactive Oxide Fillers

Materials

Laura Fiocco²  Hamada Elsayed²  Letizia Ferroni¹  Chiara Gardin¹  Barbara Zavan¹  Enrico Bernardo² 

[1] Department of Biomedical Sciences, University of Padova, Via Ugo Bassi 58/B, Padova 35131, Italy; E-Mails:;Department of Industrial Engineering, University of Padova, Via Marzolo 9, Padova 35131, Italy; E-Mails:

关键词: polymer-derived ceramics;    bioactivity;    wollastonite;    diopside;    glass-ceramic;   

DOI  :  10.3390/ma8052480

来源: mdpi

【 摘 要 】

Wollastonite (CaSiO₃) and diopside (CaMgSi₂O₆) silicate ceramics have been widely investigated as highly bioactive materials, suitable for bone tissue engineering applications. In the present paper, highly porous glass-ceramic foams, with both wollastonite and diopside as crystal phases, were developed from the thermal treatment of silicone polymers filled with CaO and MgO precursors, in the form of micro-sized particles. The foaming was due to water release, at low temperature, in the polymeric matrix before ceramic conversion, mainly operated by hydrated sodium phosphate, used as a secondary filler. This additive proved to be “multifunctional”, since it additionally favored the phase development, by the formation of a liquid phase upon firing, in turn promoting the ionic interdiffusion. The liquid phase was promoted also by the incorporation of powders of a glass crystallizing itself in wollastonite and diopside, with significant improvements in both structural integrity and crushing strength. The biological characterization of polymer-derived wollastonite-diopside foams, to assess the bioactivity of the samples, was performed by means of a cell culture test. The MTT assay and LDH activity tests gave positive results in terms of cell viability.

【 授权许可】

CC BY   
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