Addisonian Crisis after Missed Diagnosis of Posttraumatic Hypopituitarism

Journal of Clinical Medicine

Christine Streetz-van der Werf¹  Wolfram Karges¹  Marcus Blaum³  Ilonka Kreitschmann-Andermahr⁴  Günter Stalla² 

[1] Division of Endocrinology and Diabetes, RWTH Aachen University, 52062 Aachen, Germany; E-Mails:Division of Endocrinology and Diabetes, RWTH Aachen University, 52062 Aachen, Germany;;Department of Neuroradiology, RWTH Aachen University, 52062 Aachen, Germany; E-Mail:;Department of Neurosurgery, University Hospital Essen, 45147 Essen, Germany

关键词: traumatic brain injury;    hypopituitarism;    neuroendocrine dysfunction;    hypocortisolism;    Addisonian crisis;   

DOI  :  10.3390/jcm4050965

来源: mdpi

【 摘 要 】

We report a case of a previously undiagnosed panhypopituitarism initially presenting as a full-blown Addisonian crisis with hypoglycemia, hyponatremia, hypotension and neuropsychological symptoms, more than 30 years after a severe traumatic brain injury (TBI). The patient also displayed clearly visible pathognomonic clinical signs of long-standing pituitary dysfunction. The case highlights the importance of being aware of endocrine sequelae even decades after serious TBI.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.