Microwave-Assisted Synthesis of Glutathione-Capped CdTe/CdSe Near-Infrared Quantum Dots for Cell Imaging

International Journal of Molecular Sciences

Xiaogang Chen¹  Liang Li¹  Yongxian Lai²  Jianna Yan²  Yichen Tang¹  Xiuli Wang¹ 

[1] Department of Dermatologic Surgery, Shanghai Skin Disease Hospital, Shanghai 200443, China;

关键词: biomaterials;    semiconductors;    near-infrared;    core/shell;    quantum dots;    glutathione;    molecular imaging;   

DOI  :  10.3390/ijms160511500

来源: mdpi

【 摘 要 】

These glutathione (GSH)-conjugated CdTe/CdSe core/shell quantum dot (QD) nanoparticles in aqueous solution were synthesized using a microwave-assisted approach. The prepared type II core/shell QD nanoparticles were characterized by UV–Vis absorption, photoluminescence (PL) spectroscopy, X-ray powder diffraction (XRD) and high-resolution transmission electron microscopy (HR-TEM). Results revealed that the QD nanoparticles exhibited good dispersity, a uniform size distribution and tunable fluorescence emission in the near-infrared (NIR) region. In addition, these nanoparticles exhibited good biocompatibility and photoluminescence in cell imaging. In particular, this type of core/shell NIR QDs may have potential applications in molecular imaging.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.