A Perspective on the Enhancer Dependent Bacterial RNA Polymerase

Biomolecules

Nan Zhang²  Martin Buck¹  Sivaramesh Wigneshweraraj² 

[1] Department of Life Sciences, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, London SW7 2AZ, UK; E-Mail

关键词: RNA polymerase;    Sigma54;    transcription;    AAA+ ATPase;   

DOI  :  10.3390/biom5021012

来源: mdpi

【 摘 要 】

Here we review recent findings and offer a perspective on how the major variant RNA polymerase of bacteria, which contains the sigma54 factor, functions for regulated gene expression. We consider what gaps exist in our understanding of its genetic, biochemical and biophysical functioning and how they might be addressed.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.