Regulation of Transcription Elongation and Termination

Biomolecules

Robert S. Washburn²  Max E. Gottesman²  Deborah M. Hinton¹ 

[1] Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA; E-Mail;Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA; E-Mail:

关键词: transcription elongation;    transcription pausing;    transcription termination;    Nus factors;    transcription antitermination;    transcription-translation coupling;   

DOI  :  10.3390/biom5021063

来源: mdpi

【 摘 要 】

This article will review our current understanding of transcription elongation and termination in E. coli. We discuss why transcription elongation complexes pause at certain template sites and how auxiliary host and phage transcription factors affect elongation and termination. The connection between translation and transcription elongation is described. Finally we present an overview indicating where progress has been made and where it has not.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.