Nanotoxicology of Metal Oxide Nanoparticles

Metals

Amedea B. Seabra¹  Nelson Durán² 

[1] Exact and Earth Sciences Department, Universidade Federal de São Paulo, Rua São Nicolau, 210, Diadema, São Paulo 0991330, Brazil;Laboratory of Nanomaterials Synthesis and Biological Interactions (NanoBioss), Institute of Chemistry, Universidade Estadual de Campinas, Campinas, São Paulo 13083970, Brazil; E-Mail:

关键词: nanotoxicity;    metal oxide nanoparticles;    biogenic nanoparticles;    cytotoxicity;    in vivo toxicity and ecotoxicity;   

DOI  :  10.3390/met5020934

来源: mdpi

【 摘 要 】

This review discusses recent advances in the synthesis, characterization and toxicity of metal oxide nanoparticles obtained mainly through biogenic (green) processes. The in vitro and in vivo toxicities of these oxides are discussed including a consideration of the factors important for safe use of these nanomaterials. The toxicities of different metal oxide nanoparticles are compared. The importance of biogenic synthesized metal oxide nanoparticles has been increasing in recent years; however, more studies aimed at better characterizing the potent toxicity of these nanoparticles are still necessary for nanosafely considerations and environmental perspectives. In this context, this review aims to inspire new research in the design of green approaches to obtain metal oxide nanoparticles for biomedical and technological applications and to highlight the critical need to fully investigate the nanotoxicity of these particles.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.