Circulating Long Noncoding RNA as a Potential Target for Prostate Cancer

International Journal of Molecular Sciences

Yin-Jie Su²  Jin Yu¹  Ya-Qin Huang¹  Jin Yang¹ 

[1] Department of Cell Biology, the Third Military Medical University, Chongqing 400038, China; E-Mails:;Trainee Brigade, the Third Military Medical University, Chongqing 400038, China; E-Mail:

关键词: long noncoding RNA;    prostate cancer;    biomarker;    therapeutic target;   

DOI  :  10.3390/ijms160613322

来源: mdpi

【 摘 要 】

Prostate cancer is considered the second most common visceral malignancy in men in Western countries. Its emergence is largely due to the coordination of a malignant network, and long noncoding RNA has been recently demonstrated to play a critical role in prostate carcinogenesis. The aberrant expression of long noncoding RNA in prostate cancer patients is strongly associated with diagnosis, risk stratification and carcinogenesis, information that provides new insight into the complicated intracellular milieu of prostate cancer. This review focuses mainly on literature evidence for the role of long noncoding RNA in prostate cancer, which may suggest novel strategies for its prognosis, diagnosis and clinical treatment.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.