Therapeutic Effects of Bee Venom on Immunological and Neurological Diseases

Toxins

Deok-Sang Hwang¹  Sun Kwang Kim²  Hyunsu Bae² 

[1] Department of Korean Medicine Obstetrics and Gynecology, College of Korean Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, Korea; E-Mail:;Department of Physiology, College of Korean Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, Korea; E-Mail:

关键词: Bee Venom;    immunological diseases;    neurological diseases;   

DOI  :  10.3390/toxins7072413

来源: mdpi

【 摘 要 】

Bee Venom (BV) has long been used in Korea to relieve pain symptoms and to treat inflammatory diseases, such as rheumatoid arthritis. The underlying mechanisms of the anti-inflammatory and analgesic actions of BV have been proved to some extent. Additionally, recent clinical and experimental studies have demonstrated that BV and BV-derived active components are applicable to a wide range of immunological and neurodegenerative diseases, including autoimmune diseases and Parkinson’s disease. These effects of BV are known to be mediated by modulating immune cells in the periphery, and glial cells and neurons in the central nervous system. This review will introduce the scientific evidence of the therapeutic effects of BV and its components on several immunological and neurological diseases, and describe their detailed mechanisms involved in regulating various immune responses and pathological changes in glia and neurons.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.