Nutrients | |
Acute and Chronic Effects of Dietary Lactose in Adult Rats Are not Explained by Residual Intestinal Lactase Activity | |
Bert J. M. van de Heijning1  Diane Kegler2  Lidewij Schipper2  Eline Voogd2  Annemarie Oosting2  | |
[1] Danone Nutricia Research, PO Box 80141, 3508 TC Utrecht, The Netherlands; | |
关键词: digestion; lactose; lactase; galactosyl xylose; infant milk formula; rats; | |
DOI : 10.3390/nu7075237 | |
来源: mdpi | |
【 摘 要 】
Neonatal rats have a high intestinal lactase activity, which declines around weaning. Yet, the effects of lactose-containing products are often studied in adult animals. This report is on the residual, post-weaning lactase activity and on the short- and long-term effects of lactose exposure in adult rats. Acutely, the postprandial plasma response to increasing doses of lactose was studied, and chronically, the effects of a 30% lactose diet fed from postnatal (PN) Day 15 onwards were evaluated. Intestinal lactase activity, as assessed both
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190009675ZK.pdf | 594KB | download |