Nutrients | |
Serum Concentrations of Trace Elements in Patients with Tuberculosis and Its Association with Treatment Outcome | |
Rihwa Choi2  Hyoung-Tae Kim2  Yaeji Lim3  Min-Ji Kim4  O Jung Kwon1  Kyeongman Jeon1  Hye Yun Park1  Byeong-Ho Jeong1  Won-Jung Koh1  | |
[1] Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro, Gangnam-Gu, Seoul 135-710, Korea; E-Mails:;Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro, Gangnam-Gu, Seoul 135-710, Korea; E-Mails:;Biostatistics and Clinical Epidemiology Center, Samsung Medical Center, 81 Irwon-Ro, Gangnam-Gu, Seoul 135-710, Korea; E-Mail:;Biostatistics team, Samsung Biomedical Research Institute, 81 Irwon-Ro, Gangnam-Gu, Seoul 135-710, Korea; E-Mail: | |
关键词: tuberculosis; trace elements; inductively coupled plasma-mass spectrometry; Korea; | |
DOI : 10.3390/nu7075263 | |
来源: mdpi | |
【 摘 要 】
Deficiencies in essential trace elements are associated with impaired immunity in tuberculosis infection. However, the trace element concentrations in the serum of Korean patients with tuberculosis have not yet been investigated. This study aimed to compare the serum trace element concentrations of Korean adult patients with tuberculosis with noninfected controls and to assess the impact of serum trace element concentration on clinical outcome after antituberculosis treatment. The serum concentrations of four trace elements in 141 consecutively recruited patients with tuberculosis and 79 controls were analyzed by inductively coupled plasma-mass spectrometry. Demographic characteristics were also analyzed. Serum cobalt and copper concentrations were significantly higher in patients with tuberculosis compared with controls, while zinc and selenium concentrations were significantly lower (
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190009322ZK.pdf | 1505KB | download |