The Antioxidant Activity and Their Major Antioxidant Compounds from Acanthopanax senticosus and A. koreanum

Molecules

Young-Hyun Kim⁴  Myoung Lae Cho⁴  Dan-Bi Kim⁴  Gi-Hae Shin⁴  Jin-Ha Lee⁴  Jong Seok Lee²  Sun-Ok Park¹  Sang-Jong Lee¹  Hyun Mu Shin³  Ok-Hwan Lee⁴ 

[1] STR Biotech Co., LTD, Gangwon 200-160, Korea; E-Mails:;National Institute of Biological Resources, Incheon 404-708, Korea; E-Mail:;Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01605, USA; E-Mail:;Department of Food Science and Biotechnology, Kangwon National University, Chuncheon 200-701, Korea; E-Mails:

关键词: Acanthopanax senticosus;    method validation;    antioxidant activity;    chlorogenic acid;    caffeic acid;   

DOI  :  10.3390/molecules200713281

来源: mdpi

【 摘 要 】

The antioxidant activity and chlorogenic acid and caffeic acid contents were investigated from different parts of Acanthopanax senticosus and A. koreanum. Antioxidant activity was assessed by various in vitro assays such as DPPH, ABTS, FRAP, reducing power assays and ORAC, and the chlorogenic acid and caffeic acid were validated by HPLC chromatography. Among the various extracts, the fruit extracts of A. senticosus and A. koreanum exhibited strongest antioxidant activities including ABTS, FRAP, reducing power and ORAC, however, strongest DPPH radical scavenging activity was observed from the leaf extract of A. senticosus. In addition, the antioxidant activities of various extracts were correlated with total phenolic and proanthocyanidin contents. The major phenolic contents from various parts of these plants observed that leaf extract of A. senticosus expressed higher levels of chlorogenic acid (14.86 mg/dry weigh g) and caffeic acid (3.09 mg/dry weigh g) than other parts. Therefore, these results suggest that the leaf of A. senticosus may be an excellent natural source for functional foods and pharmaceutical agents, and the validated method was useful for the quality control of A. senticosus.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.