68Ga-Based Radiopharmaceuticals: Production and Application Relationship

Molecules

Irina Velikyan¹ 

[1] Section of Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, Uppsala SE-751 85, Sweden; E-Mail:

关键词: positron emission tomography;    ⁶⁸Ga;    chemistry;    receptor targeting;    peptide;    GMP;    dosimetry;   

DOI  :  10.3390/molecules200712913

来源: mdpi

【 摘 要 】

The contribution of ⁶⁸Ga to the promotion and expansion of clinical research and routine positron emission tomography (PET) for earlier better diagnostics and individualized medicine is considerable. The potential applications of ⁶⁸Ga-comprising imaging agents include targeted, pre-targeted and non-targeted imaging. This review discusses the key aspects of the production of ⁶⁸Ga and ⁶⁸Ga-based radiopharmaceuticals in the light of the impact of regulatory requirements and endpoint pre-clinical and clinical applications.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.