Recent Developments and Biological Activities of N-Substituted Carbazole Derivatives: A Review

Molecules

Maryam Bashir¹  Afifa Bano¹  Abdul Subhan Ijaz¹  Bashir Ahmad Chaudhary¹ 

关键词: N-substituted carbazoles;    antimicrobial;    anticancer;    neuroprotective;   

DOI  :  10.3390/molecules200813496

来源: mdpi

【 摘 要 】

Carbazoles represent an important class of heterocycles. These have been reported to exhibit diverse biological activities such as antimicrobial, antitumor, antiepileptic, antihistaminic, antioxidative, anti-inflammatory, antidiarrhoeal, analgesic, neuroprotective and pancreatic lipase inhibition properties. A series of carbazole derivatives such as N-substituted carbazoles, benzocarbazoles, furocarbazoles, pyrrolocarbazoles, indolocarbazoles, imidazocarbazoles, etc. have been synthesized. The N-substituted derivatives have gained the attention of researchers due to their therapeutic potential against neurological disorders and cell proliferation. Herein an attempt is made to review the medicinal importance of recently synthesized N-substituted carbazoles.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.