International Journal of Molecular Sciences | |
BMP9-Induced Survival Effect in Liver Tumor Cells Requires p38MAPK Activation | |
Mar Garc-Álvaro2  Annalisa Addante2  Cesáreo Roncero2  Margarita Fernández2  Isabel Fabregat1  Aránzazu Sánchez2  Blanca Herrera2  | |
[1] Bellvitge Biomedical Research Institute (IDIBELL) and University of Barcelona (UB), L’Hospitalet de Llobregat, Barcelona 08908, Spain; E-Mail:;Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, Complutense University of Madrid. San Carlos Clinical Hospital Health Research Institute (IdISSC), Plaza Ramón y Cajal S/N, Madrid 28040, Spain; E-Mails: | |
关键词: BMP9; non-Smad; apoptosis; liver cancer; p38MAPK; PI3K; | |
DOI : 10.3390/ijms160920431 | |
来源: mdpi | |
【 摘 要 】
The study of bone morphogenetic proteins (BMPs) role in tumorigenic processes, and specifically in the liver, has gathered importance in the last few years. Previous studies have shown that BMP9 is overexpressed in about 40% of hepatocellular carcinoma (HCC) patients.
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
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