Influence of the Systemic Application of Blue–Green Spirulina platensis Algae on the Cutaneous Carotenoids and Elastic Fibers in Vivo

Cosmetics

Maxim E. Darvin¹  Sora Jung¹  Sabine Schanzer¹  Heike Richter¹  Elke Kurth²  Gisela Thiede¹  Martina C. Meinke¹  Juergen Lademann¹ 

[1] Department of Dermatology, Venerology and Allergology, Center of Experimental and Applied Cutaneous, Physiology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany; E-Mails:;Institute for Food and Environmental Research (ILU e.V.), Arthur-Scheunert-Allee 40-41, Nuthetal 14558, Germany; E-Mail:

关键词: Stratum corneum;    protection;    antioxidants;    resonance Raman spectroscopy;    two-photon microscopy;    collagen;    elastin;   

DOI  :  10.3390/cosmetics2030302

来源: mdpi

【 摘 要 】

The objective of the study was to investigate the influence of a food supplement rich in antioxidants on the antioxidant status of the skin. For this reason, the blue-green algae Spirulina platensis powder was used for oral application during eight weeks. The effect of oral application of the antioxidant-containing Spirulina platensis on characteristic skin aging parameters, e.g., concentration of cutaneous carotenoids and the collagen/elastin index (SAAID), was investigated in vivo. A significant average increase from 2.67 ± 0.86 arb. units to 3.25 ± 0.93 arb. units (p < 0.001) in the cutaneous carotenoid concentration was detected subsequent to oral application of the carotenoid-containing Spirulina platensis powder, showing a significant improvement of the antioxidant status of the skin. A slight but not significant increase (p = 0.33) in the dermal SAAID mean values was measured from −0.54 ± 0.11 to −0.51 ± 0.11 subsequent to oral intake of Spirulina platensis powder.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.