An Evaluation on the Effect of Health Education and of Low-Dose Statin in Dyslipidemia among Low-Income Rural Uyghur Adults in Far Western China: A Comprehensive Intervention Study

International Journal of Environmental Research and Public Health

Jiaolong Ma²  Shuxia Guo¹  Rulin Ma²  Jingyu Zhang²  Jiaming Liu²  Yusong Ding²  Mei Zhang²  Heng Guo²  Jia He²  Yizhong Yan²  Lati Mu²  Shugang Li²  Qiang Niu² 

[1] Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China;

关键词: dyslipidemia;    comprehensive intervention;    rural;    evaluation;    Uyghur;   

DOI  :  10.3390/ijerph120911410

来源: mdpi

【 摘 要 】

Objective: To evaluate the effect of comprehensive intervention by health education and medical intervention to dyslipidemia Uyghur patients in low-income rural areas in Xinjiang, China. Method: A multistaged (prefecture-county-township-village) stratified cluster random sampling method was used to select participants in southern Xinjiang. Twelve villages in Jiangbazi Township in Jiashi County were chosen. These villages were randomly divided into six intervention groups and six control groups, and local Uyghur aged 18 years or older residing in the village for at least 6 months were interviewed for a baseline prevalence study and to select participants for two years of comprehensive intervention including low dose simvastatin and the effects of the interventions were observed. Results: A total of 655 participants (347 participants in the intervention groups, 308 participants in the control groups) were randomly selected from 12 villages in Jiangbazi Township, follow-up rate is 87.0%. Compared to baseline mean levels of TG and LDL-C were reduced by 1.39 mmol/L (p < 0.01) and 2.12 mmol/L (p < 0.01) respectively and levels of HDL-C increased by1.22 mmol/L (p < 0.01) in the intervention group. Lipids were controlled in 38.61% of the intervention groups vs. 3.57% of the control groups (p < 0.01). Compared with baseline lipid levels, TG, TC, LDL-C and HDL-C was significantly improved, compared with it was in control groups. Conclusions: Blood lipid levels of Uygur patients with dyslipidemia can be effectively improved through health education combined with low-dose statin administration. This suggests that national strategies in public health be developed to improve the treatments to low-income rural minorities with dyslipidemia.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.