International Journal of Molecular Sciences | |
Maternal PUFA ω-3 Supplementation Prevents Neonatal Lung Injuries Induced by Hyperoxia in Newborn Rats | |
Dyuti Sharma2  Armande Subayi Nkembi2  Estelle Aubry2  Ali Houeijeh2  Laura Butruille2  Véronique Houfflin-Debarge2  Rémi Besson2  Philippe Deruelle2  Laurent Storme2  Charles Brennan1  | |
[1]EA 4489 Environnement Périnatal et Santé, Pôle Recherche Faculté de Médecine, Université Lille Nord de France, Lille 59045, France | |
[2] | |
[3]EA 4489 Environnement Périnatal et Santé, Pôle Recherche Faculté de Médecine, Université Lille Nord de France, Lille 59045, France | |
[4] E-Mails: | |
关键词: PUFA ω-3; bronchopulmonary dysplasia; prematurity; diet; | |
DOI : 10.3390/ijms160922081 | |
来源: mdpi | |
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【 摘 要 】
Bronchopulmonary dysplasia (BPD) is one of the most common complications of prematurity, occurring in 30% of very low birth weight infants. The benefits of dietary intake of polyunsaturated fatty acids ω-3 (PUFA ω-3) during pregnancy or the perinatal period have been reported. The aim of this study was to assess the effects of maternal PUFA ω-3 supplementation on lung injuries in newborn rats exposed to prolonged hyperoxia. Pregnant female Wistar rats (
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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