An Epidemiological Study of Risk Factors of Thyroid Nodule and Goiter in Chinese Women

International Journal of Environmental Research and Public Health

Lei Zheng²  Wenhua Yan²  Yue Kong¹  Ping Liang¹  Yiming Mu² 

[1] Department of Interventional Ultrasound, Chinese People’s Liberation Army General Hospital, 28 Fu Xing Road, Beijing 100853, China; E-Mail:;Department of Endocrinology, Chinese People’s Liberation Army (PLA)General Hospital, 28 Fu Xing Road, Beijing 100853, China; E-Mails:

关键词: epidemiology;    prevalence;    risk factor;    metabolic syndrome;   

DOI  :  10.3390/ijerph120911608

来源: mdpi

【 摘 要 】

Thyroid nodule (TN) and goiter are two common disorders of the thyroid. Despite their benign nature, both conditions can be associated with multiple pathologic conditions including thyroid cancer. In this study, we conducted a large-scale epidemiological study in Chinese women to identify the risk factors implicated in the occurrence of TN and goiter. We analyzed demographic data, lifestyle, medical history, body height, weight, waist circumference, body mass index (BMI), blood pressure, serum glucose and lipids. In addition, thyroid ultrasonography was performed for all subjects. Our results showed that age, menopause, waist circumference, BMI, hypertension, dyslipidemia, and hyperglycemia were associated with both TN and goiter. Furthermore, we found that the prevalence of TN was significantly affected by the medical management of hypertension. Our study suggests that postmenopausal Chinese women with advanced age, obesity, diabetes, and hypertension have an increased awareness of thyroid examination in the annual physical check. Conversely, patients with TN and goiter of the same population may have a higher incidence of age- and obesity-related metabolic disorders.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.