Candida glabrata, Friend and Foe

Journal of Fungi

Phyllix Tam²  Kirsten Gee²  Miryam Piechocinski²  Ian Macreadie¹ 

[1] School of Applied Sciences, RMIT University, Bundoora, Victoria 3083, Australia;

关键词: antifungal resistance;    azole;    candidiasis;    ergosterol;    opportunistic pathogen;    starter culture;    statins;    Torulopsis;    yeast;   

DOI  :  10.3390/jof1020277

来源: mdpi

【 摘 要 】

Candida glabrata is mostly good, but, at times, it is an opportunistic pathogen. Previously known as Torulopsis glabrata, it enjoyed a good reputation and was even present in starter cultures. Its haploid genome and lack of mating made it an attractive challenge for yeast genetics studies. However, more recently it has become better known due to its character as an emerging cause of candidiasis, and for its resistance to multidrugs that are employed for candidiasis treatment. While now classified as Candida glabrata, it is still not a good fit and tends to stand alone as a very unique yeast. In terms of sequence, it is dissimilar to other Candida yeast and most similar to Saccharomyces cerevisiae.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.