A Review of Management of Clostridium difficile Infection: Primary and Recurrence

Antibiotics

Yasmeen Vincent¹  Arif Manji¹  Kathleen Gregory-Miller¹  Christine Lee¹ 

[1] St. Joseph’s Healthcare Hamilton, 50 Charlton Ave. East, Hamilton, ON L8N 4A6, Canada; E-Mails:

关键词: recurrence;    Clostridium difficile infection;    fecal microbiota transplantation (FMT);    probiotics;    immunotherapy;    antibiotics;   

DOI  :  10.3390/antibiotics4040411

来源: mdpi

【 摘 要 】

Clostridium difficile infection (CDI) is a potentially fatal illness, especially in the elderly and hospitalized individuals. The recurrence and rates of CDI are increasing. In addition, some cases of CDI are refractory to the currently available antibiotics. The search for improved modalities for the management of primary and recurrent CDI is underway. This review discusses the current antibiotics, fecal microbiota transplantation (FMT) and other options such as immunotherapy and administration of non-toxigenic Clostridium difficile (CD) for the management of both primary and recurrent CDI.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.