Molecules | |
Antibacterial Activity, Antioxidant Effect and Chemical Composition of Propolis from the Región del Maule, Central Chile | |
Nélida Nina2  Cristina Quispe2  Felipe Jiménez-Aspee2  Cristina Theoduloz3  Gabriela Egly Feresín4  Beatriz Lima4  Elba Leiva1  Guillermo Schmeda-Hirschmann2  | |
[1] Facultad de Ciencias de la Salud, Programa de Magister en Ciencias Biomédicas, Universidad de Talca, Talca 3460000, Chile; E-Mail:;Laboratorio de Química de Productos Naturales, Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla 747, Talca 3460000, Chile; E-Mails:;Laboratorio de Cultivo Celular, Facultad de Ciencias de la Salud, Universidad de Talca, Casilla 747, Talca 3460000, Chile; E-Mail:;Instituto de Biotecnología, Facultad de Ingeniería, Universidad Nacional de San Juan, Av. Libertador General San Martin 1109 (oeste), San Juan 5400, Argentina; E-Mails: | |
关键词: propolis; antimicrobial; phenolics; flavonoids; diarylheptanoids; poilaneic acid; | |
DOI : 10.3390/molecules201018144 | |
来源: mdpi | |
【 摘 要 】
Propolis is commercialized in Chile as an antimicrobial agent. It is obtained mainly from central and southern Chile, but is used for the same purposes regardless of its origin. To compare the antimicrobial effect, the total phenolic (TP), the total flavonoid (TF) content and the phenolic composition, 19 samples were collected in the main production centers in the Región del Maule, Chile. Samples were extracted with MeOH and assessed for antimicrobial activity against Gram (+) and Gram (−) bacteria. TP and TF content, antioxidant activity by the DPPH, FRAP and TEAC methods were also determined. Sample composition was assessed by HPLD-DAD-ESI-MS/MS. Differential compounds in the samples were isolated and characterized. The antimicrobial effect of the samples showed MICs ranging from 31.5 to > 1000 µg/mL. Propolis from the central valley was more effective as antibacterial than those from the coastal area or Andean slopes. The samples considered of interest (MIC ≤ 62.5 µg/mL) showed effect on
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190005281ZK.pdf | 1920KB | download |