Man-Made Synthetic Receptors for Capture and Analysis of Ochratoxin A

Toxins

Claudio Baggiani¹  Cristina Giovannoli¹  Laura Anfossi¹ 

[1] Laboratory of Bioanalytical Chemistry, Department of Chemistry, University of Torino, Torino 10125, Italy; E-Mails:

关键词: mycotoxin;    Ochratoxin A;    molecularly imprinted polymer;    aptamer;    oligosorbent;    peptide library;    binding peptide;    solid phase extraction;   

DOI  :  10.3390/toxins7104083

来源: mdpi

【 摘 要 】

Contemporary analytical methods have the sensitivity required for Ochratoxin A detection and quantification, but direct application of these methods on real samples can be rarely performed because of matrix complexity. Thus, efficient sample pre-treatment methods are needed. Recent years have seen the increasing use of artificial recognition systems as a viable alternative to natural receptors, because these materials seem to be particularly suitable for applications where selectivity for Ochratoxin A is essential. In this review, molecularly imprinted polymers, aptamers and tailor-made peptides for Ochratoxin A capture and analysis with particular attention to solid phase extraction applications will be discussed.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.