New Nanomaterials and Luminescent Optical Sensors for Detection of Hydrogen Peroxide

Chemosensors

Natalia A. Burmistrova²  Olga A. Kolontaeva²  Axel Duerkop¹ 

[1]Institute of Analytical Chemistry, Chemo- and Biosensors, University of Regensburg, Regensburg 93040, Germany

[2]Institute of Chemistry, Saratov State University, Saratov 410012, Russia

[3] E-Mails:

关键词: sensor;    optical;    hydrogen peroxide;    luminescence;    fluorescence;    membrane;    nanoparticle;    microplate;    nanodot;    quantum dots;   

DOI  :  10.3390/chemosensors3040253

来源: mdpi

【 摘 要 】

Accurate methods that can continuously detect low concentrations of hydrogen peroxide (H₂O₂) have a huge application potential in biological, pharmaceutical, clinical and environmental analysis. Luminescent probes and nanomaterials are used for fabrication of sensors for H₂O₂ that can be applied for these purposes. In contrast to previous reviews focusing on the chemical design of molecular probes for H₂O₂, this mini-review highlights the latest luminescent nanoparticular materials and new luminescent optical sensors for H₂O₂ in terms of the nanomaterial composition and luminescent receptor used in the sensors. The nanomaterial section is subdivided into schemes based on gold nanoparticles, polymeric nanoparticles with embedded enzymes, probes showing aggregation-induced emission enhancement, quantum dots, lanthanide-based nanoparticles and carbon based nanomaterials, respectively. Moreover, the sensors are ordered according to the type of luminescent receptor used within the sensor membranes. Among them are lanthanide complexes, metal-ligand complexes, oxidic nanoparticles and organic dyes. Further, the optical sensors are confined to those that are capable to monitor the concentration of H₂O₂ in a sample over time or are reusable. Optical sensors responding to gaseous H₂O₂ are not covered. All nanomaterials and sensors are characterized with respect to the analytical reaction towards H₂O₂, limit of detection (LOD), analytical range, electrolyte, pH and response time/incubation time. Applications to real samples are given. Finally, we assess the suitability of the nanomaterials to be used in membrane-based sensors and discuss future trends and perspectives of these sensors in biomedical research.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.