A Click Chemistry Approach towards Flavin-Cyclodextrin Conjugates—Bioinspired Sulfoxidation Catalysts

Molecules

Petra Tomanová²  Jiří Šturala²  Miloš Buděšínský¹  Radek Cibulka² 

[1] Institute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nám. 2, 166 10 Prague 6, Czech Republic;Department of Organic Chemistry, University of Chemistry and Technology, Prague, Technická 5, 166 28 Prague 6, Czech Republic;

关键词: click chemistry;    cyclodextrin;    flavin;    monooxygenase;    oxidation;    sulfoxides;    green chemistry;   

DOI  :  10.3390/molecules201119667

来源: mdpi

【 摘 要 】

A click chemistry approach based on the reaction between alkynylflavins and mono(6-azido-6-deoxy)-β-cyclodextrin has proven to be a useful tool for the synthesis of flavin-cyclodextrin conjugates studied as monooxygenase mimics in enantioselective sulfoxidations.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.