The Role of Maternal Dietary Proteins in Development of Metabolic Syndrome in Offspring

Nutrients

Alireza Jahan-Mihan¹  Judith Rodriguez²  Catherine Christie²  Marjan Sadeghi² 

[1] Department of Nutrition and Dietetics, Brook College of Health, University of North Florida, UNF Dr. Bldg 39, Room 3057A, Jacksonville, FL 32224, USA

关键词: protein;    fetal programming;    metabolic syndrome;   

DOI  :  10.3390/nu7115460

来源: mdpi

【 摘 要 】

The prevalence of metabolic syndrome and obesity has been increasing. Pre-natal environment has been suggested as a factor influencing the risk of metabolic syndrome in adulthood. Both observational and experimental studies showed that maternal diet is a major modifier of the development of regulatory systems in the offspring in utero and post-natally. Both protein content and source in maternal diet influence pre- and early post-natal development. High and low protein dams’ diets have detrimental effect on body weight, blood pressure191 and metabolic and intake regulatory systems in the offspring. Moreover, the role of the source of protein in a nutritionally adequate maternal diet in programming of food intake regulatory system, body weight, glucose metabolism and blood pressure in offspring is studied. However, underlying mechanisms are still elusive. The purpose of this review is to examine the current literature related to the role of proteins in maternal diets in development of characteristics of the metabolic syndrome in offspring.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.