Triterpenoids from the Herbs of Salicornia bigelovii

Molecules

Yu Shan¹  Huan Li¹  Fuqin Guan¹  Yu Chen¹  Min Yin¹  Ming Wang¹  Xu Feng¹  Qizhi Wang¹ 

[1] Jiangsu Key Laboratory for Bioresources of Saline Soils, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China;

关键词: Salicornia bigelovii Torr.;    nortriterpenoid saponins;    antifungal activity;   

DOI  :  10.3390/molecules201119695

来源: mdpi

【 摘 要 】

A new nortriterpene saponin, 3-O-β-d-glucuronopyranosyl-30-norolean-12,20(29)-dien-23-oxo-28-oic acid, namely bigelovii D (11), was isolated from the hydroalcoholic extract of herbs of Salicornia bigelovii along with 10 known saponins (1–10). Their chemical structures were identified on the basis of spectroscopic analyses including two-dimensional NMR and a comparison with literature data. Some of these compounds showed potent antifungal activities in vitro. Compounds 3, 4, 5, 6, 7, 10 and 11 demonstrated potent inhibitory activities against Colletotrichum gloeosporioides and compound 11 displayed broad-spectrum inhibitory activity against Alternaria alternata, A. solani, Botrytis cinerea, C. gloeosporioides, Fusarium graminearum, F. verticilloides, Thanatephorus cucumeris and Sclerotinia sclerotiorum, with EC₅₀ values ranging from 13.6 to 36.3 μg/mL.

【 授权许可】

CC BY   
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