Efficient SNP Discovery by Combining Microarray and Lab-on-a-Chip Data for Animal Breeding and Selection

Microarrays

Chao-Wei Huang¹  Yu-Tsung Lin³  Shih-Torng Ding¹  Ling-Ling Lo²  Pei-Hwa Wang¹  En-Chung Lin¹  Fang-Wei Liu³  Yen-Wen Lu³ 

[1] Department of Animal Science, National Taiwan University, Taipei 10617, Taiwan; E-Mails:;Department of Animal Science, Chinese Culture University, Taipei 11114, Taiwan; E-Mail:;Department of Bio-Industrial Mechatronics Engineering, National Taiwan University, Taipei 10617, Taiwan; E-Mails:

关键词: economic traits;    swine;    chicken;    marker-assisted selection (MAS);   

DOI  :  10.3390/microarrays4040570

来源: mdpi

【 摘 要 】

The genetic markers associated with economic traits have been widely explored for animal breeding. Among these markers, single-nucleotide polymorphism (SNPs) are gradually becoming a prevalent and effective evaluation tool. Since SNPs only focus on the genetic sequences of interest, it thereby reduces the evaluation time and cost. Compared to traditional approaches, SNP genotyping techniques incorporate informative genetic background, improve the breeding prediction accuracy and acquiesce breeding quality on the farm. This article therefore reviews the typical procedures of animal breeding using SNPs and the current status of related techniques. The associated SNP information and genotyping techniques, including microarray and Lab-on-a-Chip based platforms, along with their potential are highlighted. Examples in pig and poultry with different SNP loci linked to high economic trait values are given. The recommendations for utilizing SNP genotyping in nimal breeding are summarized.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.