Prostate Cancer Stem Cells: Research Advances

International Journal of Molecular Sciences

Dagmara Jaworska²  Wojciech Król²  Ewelina Szliszka¹ 

[1] Department of Microbiology and Immunology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, H. Jordana 19, 41-808 Zabrze, Poland

关键词: cancer stem cell;    prostate cancer;    metastasis;    castration-resistant prostate cancer;   

DOI  :  10.3390/ijms161126036

来源: mdpi

【 摘 要 】

Cancer stem cells have been defined as cells within a tumor that possesses the capacity to self-renew and to cause the heterogeneous lineages of cancer cells that comprise the tumor. Experimental evidence showed that these highly tumorigenic cells might be responsible for initiation and progression of cancer into invasive and metastatic disease. Eradicating prostate cancer stem cells, the root of the problem, has been considered as a promising target in prostate cancer treatment to improve the prognosis for patients with advanced stages of the disease.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.