Development of β Type Ti23Mo-45S5 Bioglass Nanocomposites for Dental Applications

Materials

Karolina Jurczyk³  Andrzej Miklaszewski¹  Mieczyslawa U. Jurczyk²  Mieczyslaw Jurczyk¹ 

[1] Institute of Materials Science and Engineering, Poznan University of Technology, Jana Pawla II 24, Poznan 61-138, Poland;Division of Mother’s and Child’s Health, Poznan University of Medical Sciences, Polna 33, Poznan 60-535, Poland;Department of Conservative Dentistry and Periodontology, Poznan University of Medical Sciences, Bukowska 70, Poznan 60-812, Poland;

关键词: titanium;    45S5 bioglass;    nanocomposite;    powder metallurgy;    surface properties;    etching;   

DOI  :  10.3390/ma8125441

来源: mdpi

【 摘 要 】

Titanium β-type alloys attract attention as biomaterials for dental applications. The aim of this work was the synthesis of nanostructured β type Ti23Mo-x wt % 45S5 Bioglass (x = 0, 3 and 10) composites by mechanical alloying and powder metallurgy methods and their characterization. The crystallization of the amorphous material upon annealing led to the formation of a nanostructured β type Ti23Mo alloy with a grain size of approximately 40 nm. With the increase of the 45S5 Bioglass contents in Ti23Mo, nanocomposite increase of the α-phase is noticeable. The electrochemical treatment in phosphoric acid electrolyte resulted in a porous surface, followed by bioactive ceramic Ca-P deposition. Corrosion resistance potentiodynamic testing in Ringer solution at 37 °C showed a positive effect of porosity and Ca-P deposition on nanostructured Ti23Mo 3 wt % 45S5 Bioglass nanocomposite. The contact angles of glycerol on the nanostructured Ti23Mo alloy were determined and show visible decrease for bulk Ti23Mo 3 wt % 45S5 Bioglass and etched Ti23Mo 3 wt % 45S5 Bioglass nanocomposites. In vitro tests culture of normal human osteoblast cells showed very good cell proliferation, colonization, and multilayering. The present study demonstrated that porous Ti23Mo 3 wt % 45S5 Bioglass nanocomposite is a promising biomaterial for bone tissue engineering.

【 授权许可】

CC BY   
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